In 1992, Dannii made her feature film debut in Secrets. The film revolved around five Australian teenagers who become stuck in the basement of a hotel in an attempt to see The Beatles.

In 1994, Dannii returned to television as a presenter, co-hosting in the UK the Channel 4's morning show The Big Breakfast in the UK. In 1996, she resumed her co-hosting duties, presenting the Eggs on Legs road show segment. That same year, Dannii briefly hosted the children's show Disney Time and co-hosted, with Gareth Jones, the teenage Saturday morning entertainment show It's Not Just Saturday for sixteen weeks. The show achieved high ratings, averaging over 1.5 million viewers in the UK. In 1997, she  hosted Top of the Pops, a UK music chart television programme, before returning to her music career later that year.

In April 1997, Dannii made her stage debut as Rizzo in the musical Grease: The Arena Spectacular. In Australia, the show sold over 450,000 tickets during its first season. The following year, Dannii resumed her role as Rizzo, performing in New Zealand. At the 1998 MO Awards, she was nominated for "Best Female Musical Theatre Performer" for her role. Her next theatre role was a 1999 production of Shakespeare's Macbeth at the Edinburgh Fringe Festival.  Two years later, Dannii appeared as Esmeralda in the musical production of Notre-Dame de Paris in London's West End.  At the 2002 Maxim Awards, Dannii won "Best Stage Performance" for her role. In 2001, Dannii appeared in the stage play The Vagina Monologues, which co-starred Kika Markham and Meera Syal.

In October 2004, Dannii appeared as Nightclub Owner Bunny Stigler in the film The Porter.

In February 2007, Dannii appeared as a judge on the variety show Australia's Got Talent.

In 2008, Dannii will be playing Shaunagh in the Australian film Except East Richmond.